Monomethyl auristatin E (MMAE) is an antimitotic agent which inhibits cell division by blocking the polymerisation of tubulin. The family of auristatins are synthetic analogues of the antineoplastic natural product Dolastatin 10. MMAE is 100-1000 times more potent than Doxorubicin.
Together with our European partner we realized a bulk production for MMAE, MMAF (Monomethyl Auristatine E/F) and MMAF-OMe with a purity of min. 95% (HPLC).