alpha-Conotoxin MI

Article number:

5250030

Formula:

C58H88N22O17S4

Chemical description:

Sequence: [Cys3-Cys8, Cys4-Cys14]; H-Gly-Arg-Cys-Cys-His-Pro-Ala-Cys-Gly-Lys-Asn-Tyr-Ser-Cys-NH2

Molecular weight:

1493,70 g/mol

a-conotoxins MI has been isolated from the venom of the cone snail Conus magus. This conotoxin act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. a-conotoxins MI blocks mammalian nAChR composed of a-1/d subunits with high potency and a-1/? with a low potency.

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alpha-Conotoxin MI

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