Maurotoxin

Article number:

5250027

Formula:

C178H286N52O50S7

Chemical description:

Sequence: [Cys3-Cys24, Cys9-Cys29, Cys13-Cys19, Cys31-Cys34]; H-Val-Ser-Cys-Thr-Gly-Ser-Lys-Asp-Cys-Tyr-Ala-Pro-Cys-Arg-Lys-Gln-Thr-Gly-Cys-Pro-Asn-Ala-Lys-Cys-Ile-Asn-Lys-Ser-Cys-Lys-Cys-Tyr-Gly-Cys-NH2

Molecular weight:

3613,00 g/mol

Maurotoxin is a component of the venom of Scorpio maurus palmatus. This toxin is a member of the α-KTx6.2 scorpion toxin family. It blocks voltage-gated potassium channels (KV1.1/KCNA1, KV1.2/KCNA2, and KV1.3/KCNA3) and inhibits apamin-sensitive small conductance calcium-activated channels (SK channels), particularly KCa3.1(IKca1, SK4).

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Maurotoxin

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