Article number:


CAS No.:




Molecular weight:

272,25 g/mol

Plant: found in citrus plants, especially grapefruit (Citrus ×paradisi).

  • Is responsible for the bitter taste of grapefruit
  • This substance can influence the effect of drugs, as it has an inhibitory effect on the degrading enzymes –> Effect of the drug is increased (even with small amounts of fruit, juice and other preparations from grapefruit)
  • Affected drugs include calcium antagonists, ciclosporin, protease inhibitors, terfenadine, midazolam, estrogens and caffeine
  • Special features: high bioavailability, fat-soluble, antioxidant, DNA (hereditary information) protection, stimulation of the formation of phase II enzymes

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