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Plant: found in citrus plants, especially grapefruit (Citrus ×paradisi).
- Is responsible for the bitter taste of grapefruit
- This substance can influence the effect of drugs, as it has an inhibitory effect on the degrading enzymes –> Effect of the drug is increased (even with small amounts of fruit, juice and other preparations from grapefruit)
- Affected drugs include calcium antagonists, ciclosporin, protease inhibitors, terfenadine, midazolam, estrogens and caffeine
- Special features: high bioavailability, fat-soluble, antioxidant, DNA (hereditary information) protection, stimulation of the formation of phase II enzymes
We open up new dimensions with phytochemicals Secondary phytochemicals are not essential for plants, but still perform important functions. These substances serve as protection against herbivores or pathogens, but also ...
With more than 1200 substances (reference substances) Cfm Oskar Tropitzsch GmbH offers a broad range of herbal reference standards for the natural products chemistry. The portfolio consists substances from all ...