Sarafotoxin-C

Article number:

5250037

Formula:

C103H147N27O37S5

Chemical description:

Sequence: [Cys1-Cys15, Cys3-Cys11]; H-Cys-Thr-Cys-Asn-Asp-Met-Thr-Asp-Glu-Glu-Cys-Leu-Asn-Phe-Cys-His-Gln-Asp-Val-Ile-Trp-OH

Molecular weight:

2515,80 g/mol

Sarafotoxin-C has been isolated from the venom of the Snaker Atractaspis engaddensis. This toxin presents a vasoconstrictor activity. This compound has a close structural homology to the endothelin family. Sarafotoxin-A causes cardiac arrest probably as a result of coronary vasospasm. LD50 is 0.3 mg/kg by intravenous injection for sarafotoxin-C.

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Sarafotoxin-C

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