Stichodactyla toxin

Article number:

5250028

Chemical description:

Sequence: [Cys3-Cys35, Cys12-Cys28, Cys17-Cys32]; H-Arg-Ser-Cys-Ile-Asp-Thr-Ile-Pro-Lys-Ser-Arg-Cys-Thr-Ala-Phe-Gln-Cys-Lys-His-Ser-Met-Lys-Tyr-Arg-Leu-Ser-Phe-Cys-Arg-Lys-Thr-Cys-Gly-Thr-Cys-OH

Synonyms:

ShK

Molecular weight:

4178,90 g/mol

ShK has been isolated from the venom of the sCarribean sea anemone Stoichactis helianthus. This toxin inhibits voltage-dependent potassium channels. Inhibits Kv1.3 (KCNA3) potently and also blocks Kv1.1 (KCNA1), Kv1.4 (KCNA4), and Kv1.6 (KCNA6) at subnanomolar concentrations.

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Stichodactyla toxin

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