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Reagents for ADCs
Cfm Oskar Tropitzsch offers ecxept payloads also other important reagents for the Conjugation of ADCs. One example is Dithiothreitol (DTT, Clealand`s reagent). DTT is a redox reagent in molecular biology. DTT preserves proteins of interiors of cells in their functional form by avoiding the oxidation of Sulfhidril-groups (SH-) into disulifidbridges through atmospheric oxygen. On the other hand the convolution of proteins whose structure is stabilised by disulfidbridges may be destroyed by their reduction.