{"id":86733,"date":"2024-11-06T11:14:13","date_gmt":"2024-11-06T10:14:13","guid":{"rendered":"https:\/\/www.cfmot.de\/active-ingredient-of-the-month-november-histamine-dihydrochloride\/"},"modified":"2024-11-06T11:17:49","modified_gmt":"2024-11-06T10:17:49","slug":"active-ingredient-of-the-month-november-histamine-dihydrochloride","status":"publish","type":"post","link":"https:\/\/www.cfmot.de\/en\/active-ingredient-of-the-month-november-histamine-dihydrochloride\/","title":{"rendered":"Active ingredient of the month November: histamine dihydrochloride"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"86733\" class=\"elementor elementor-86733 elementor-86721\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-aa2c39e elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"aa2c39e\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-877c835\" data-id=\"877c835\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-9a633e0 elementor-widget elementor-widget-text-editor\" data-id=\"9a633e0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>The active ingredient of the month for November is histamine dihydrochloride. The main area of application for this is the treatment of acute myeloid leukemia (AML) in combination with interleukin-2 (IL-2).<\/p><p>Histamine dihydrochloride is mainly used in maintenance therapy for adult patients with AML who are in initial remission. It is administered in specific treatment cycles, often in combination with IL-2. This is intended to strengthen the immune response on the one hand and prevent the recurrence of the disease on the other.<\/p><h4>Effective in myeloid leukemia<\/h4><p>Histamine dihydrochloride inhibits the production of reactive oxygen species (ROS), which are produced by certain immune cells. These ROS can impair the function of lymphocytes, which are of great importance for fighting leukemia cells. By inhibiting ROS production, histamine dihydrochloride protects lymphocytes while optimizing their ability to destroy leukemia cells.<\/p><p>The active ingredient is administered in the form of subcutaneous injections. The therapy consists of several cycles. Each cycle lasts 21 days and includes a treatment-free period. Histamine dihydrochloride is an important component in the treatment of AML in the form of targeted immunotherapy.<\/p><h4>Also important for allergy diagnostics and biomedical research<\/h4><p>In addition to cancer therapy, there are other areas of application for this active substance. It plays a major role in allergy diagnostics and biomedical research.<\/p><ul><li><strong>Prick tests:<\/strong> Here, histamine dihydrochloride is used as a positive control to diagnose allergic reactions.<\/li><li><strong>Research:<\/strong> In research, it is intended to demonstrate the role of histamine in various physiological processes, for example in the study of reactions to antigens.<\/li><li><strong>Orthograde Neurotransmitter:<\/strong> Histamine dihydrochloride is used as an orthograde neurotransmitter to generate excitatory postsynaptic potentials.<\/li><\/ul><p>\u00a0<\/p><p><strong>\u21d2 If you are interested in <a href=\"https:\/\/www.cfmot.de\/en\/produkt\/histamine-dihydrochloride\/\">Histamine Dihydrochloride<\/a>, please do not hesitate to contact us.<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-8bb761b elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"8bb761b\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-87d9020\" data-id=\"87d9020\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-5308c2e elementor-widget elementor-widget-image\" data-id=\"5308c2e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"201\" height=\"164\" src=\"https:\/\/www.cfmot.de\/wp-content\/uploads\/2024\/11\/Struktur-Histamin-1.jpg\" class=\"attachment-medium size-medium wp-image-86728\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>The active ingredient of the month for November is histamine dihydrochloride. The main area of application for this is the treatment of acute myeloid leukemia (AML) in combination with interleukin-2 (IL-2). Histamine dihydrochloride is mainly used in maintenance therapy for adult patients with AML who are in initial remission. It is administered in specific treatment [&hellip;]<\/p>\n","protected":false},"author":10,"featured_media":86723,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[48,139],"tags":[],"class_list":["post-86733","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog-en-2","category-pharmaceutical-products"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.0 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Active ingredient of the month November: histamine dihydrochloride - Cfm Oskar Tropitzsch GmbH<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.cfmot.de\/en\/active-ingredient-of-the-month-november-histamine-dihydrochloride\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Active ingredient of the month November: histamine dihydrochloride - Cfm Oskar Tropitzsch GmbH\" \/>\n<meta property=\"og:description\" content=\"The active ingredient of the month for November is histamine dihydrochloride. The main area of application for this is the treatment of acute myeloid leukemia (AML) in combination with interleukin-2 (IL-2). Histamine dihydrochloride is mainly used in maintenance therapy for adult patients with AML who are in initial remission. It is administered in specific treatment [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.cfmot.de\/en\/active-ingredient-of-the-month-november-histamine-dihydrochloride\/\" \/>\n<meta property=\"og:site_name\" content=\"Cfm Oskar Tropitzsch GmbH\" \/>\n<meta property=\"article:published_time\" content=\"2024-11-06T10:14:13+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-11-06T10:17:49+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.cfmot.de\/wp-content\/uploads\/2024\/11\/Histamin.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1600\" \/>\n\t<meta property=\"og:image:height\" content=\"1000\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Karin Bayer\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Karin Bayer\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.cfmot.de\\\/en\\\/active-ingredient-of-the-month-november-histamine-dihydrochloride\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.cfmot.de\\\/en\\\/active-ingredient-of-the-month-november-histamine-dihydrochloride\\\/\"},\"author\":{\"name\":\"Karin Bayer\",\"@id\":\"https:\\\/\\\/www.cfmot.de\\\/en\\\/#\\\/schema\\\/person\\\/0192b39a358835d45c94562d47c033c7\"},\"headline\":\"Active ingredient of the month November: histamine dihydrochloride\",\"datePublished\":\"2024-11-06T10:14:13+00:00\",\"dateModified\":\"2024-11-06T10:17:49+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.cfmot.de\\\/en\\\/active-ingredient-of-the-month-november-histamine-dihydrochloride\\\/\"},\"wordCount\":291,\"image\":{\"@id\":\"https:\\\/\\\/www.cfmot.de\\\/en\\\/active-ingredient-of-the-month-november-histamine-dihydrochloride\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.cfmot.de\\\/wp-content\\\/uploads\\\/2024\\\/11\\\/Histamin.jpg\",\"articleSection\":[\"Blog\",\"Pharmaceutical Products\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.cfmot.de\\\/en\\\/active-ingredient-of-the-month-november-histamine-dihydrochloride\\\/\",\"url\":\"https:\\\/\\\/www.cfmot.de\\\/en\\\/active-ingredient-of-the-month-november-histamine-dihydrochloride\\\/\",\"name\":\"Active ingredient of the month November: histamine dihydrochloride - 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