{"id":64731,"date":"2019-02-25T16:52:59","date_gmt":"2019-02-25T15:52:59","guid":{"rendered":"https:\/\/www.cfmot.de\/produkt\/bergamottin-2\/"},"modified":"2023-03-07T16:39:13","modified_gmt":"2023-03-07T15:39:13","slug":"bergamottin-2","status":"publish","type":"produkt","link":"https:\/\/www.cfmot.de\/en\/produkt\/bergamottin-2\/","title":{"rendered":"Bergamottin"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"64731\" class=\"elementor elementor-64731 elementor-64730\" data-elementor-post-type=\"produkt\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-300e1b8 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"300e1b8\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-942631d\" data-id=\"942631d\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-d263cd3 elementor-widget elementor-widget-text-editor\" data-id=\"d263cd3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Plant:<\/strong> occurs naturally in bergamot (Citrus bergamia) and grapefruit (Citrus \u00d7paradisi), also in other citrus fruits, but in small amounts.<\/p><ul><li>Is a chemical compound from the group of furanocoumarins with geraniol side chain<\/li><li>Bergamottin is an inhibitor of CYP3A4 and is partly responsible for the slowed degradation of some drugs after consumption of grapefruit &#8211;&gt; patient is often warned against grapefruit juice when taking drugs<\/li><li>Bergamottin increases oral bioavailability and plasma concentrations of these drugs<\/li><li>Can be isolated from grapefruit juice by extraction with ethyl acetate followed by silica gel chromatography and HPLC.<\/li><li>Example of use of this effect in topical drugs, is the concomitant use of ritonavir, a potent inhibitor of CYP3A4 and CYP2D6 isoforms of cytochrome P450, with other antiretroviral drugs<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"featured_media":0,"template":"","produktgruppe":[108],"class_list":["post-64731","produkt","type-produkt","status-publish","hentry","produktgruppe-reference-substances"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Bergamottin - Cfm Oskar Tropitzsch GmbH<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.cfmot.de\/en\/produkt\/bergamottin-2\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Bergamottin - Cfm Oskar Tropitzsch GmbH\" \/>\n<meta property=\"og:description\" content=\"Plant: occurs naturally in bergamot (Citrus bergamia) and grapefruit (Citrus \u00d7paradisi), also in other citrus fruits, but in small amounts. Is a chemical compound from the group of furanocoumarins with geraniol side chain Bergamottin is an inhibitor of CYP3A4 and is partly responsible for the slowed degradation of some drugs after consumption of grapefruit &#8211;&gt; [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.cfmot.de\/en\/produkt\/bergamottin-2\/\" \/>\n<meta property=\"og:site_name\" content=\"Cfm Oskar Tropitzsch GmbH\" \/>\n<meta property=\"article:modified_time\" content=\"2023-03-07T15:39:13+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.cfmot.de\\\/en\\\/produkt\\\/bergamottin-2\\\/\",\"url\":\"https:\\\/\\\/www.cfmot.de\\\/en\\\/produkt\\\/bergamottin-2\\\/\",\"name\":\"Bergamottin - Cfm Oskar Tropitzsch GmbH\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.cfmot.de\\\/en\\\/#website\"},\"datePublished\":\"2019-02-25T15:52:59+00:00\",\"dateModified\":\"2023-03-07T15:39:13+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.cfmot.de\\\/en\\\/produkt\\\/bergamottin-2\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.cfmot.de\\\/en\\\/produkt\\\/bergamottin-2\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.cfmot.de\\\/en\\\/produkt\\\/bergamottin-2\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.cfmot.de\\\/en\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Phytochemicals\",\"item\":\"https:\\\/\\\/www.cfmot.de\\\/en\\\/produktgruppe\\\/phytochemicals\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Reference Substances\",\"item\":\"https:\\\/\\\/www.cfmot.de\\\/en\\\/produktgruppe\\\/reference-substances\\\/\"},{\"@type\":\"ListItem\",\"position\":4,\"name\":\"Bergamottin\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.cfmot.de\\\/en\\\/#website\",\"url\":\"https:\\\/\\\/www.cfmot.de\\\/en\\\/\",\"name\":\"Cfm Oskar Tropitzsch GmbH\",\"description\":\"Chemikalien, Feinchemikalien, Metallverbindungen\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.cfmot.de\\\/en\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Bergamottin - Cfm Oskar Tropitzsch GmbH","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.cfmot.de\/en\/produkt\/bergamottin-2\/","og_locale":"en_US","og_type":"article","og_title":"Bergamottin - Cfm Oskar Tropitzsch GmbH","og_description":"Plant: occurs naturally in bergamot (Citrus bergamia) and grapefruit (Citrus \u00d7paradisi), also in other citrus fruits, but in small amounts. Is a chemical compound from the group of furanocoumarins with geraniol side chain Bergamottin is an inhibitor of CYP3A4 and is partly responsible for the slowed degradation of some drugs after consumption of grapefruit &#8211;&gt; [&hellip;]","og_url":"https:\/\/www.cfmot.de\/en\/produkt\/bergamottin-2\/","og_site_name":"Cfm Oskar Tropitzsch GmbH","article_modified_time":"2023-03-07T15:39:13+00:00","twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.cfmot.de\/en\/produkt\/bergamottin-2\/","url":"https:\/\/www.cfmot.de\/en\/produkt\/bergamottin-2\/","name":"Bergamottin - Cfm Oskar Tropitzsch GmbH","isPartOf":{"@id":"https:\/\/www.cfmot.de\/en\/#website"},"datePublished":"2019-02-25T15:52:59+00:00","dateModified":"2023-03-07T15:39:13+00:00","breadcrumb":{"@id":"https:\/\/www.cfmot.de\/en\/produkt\/bergamottin-2\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.cfmot.de\/en\/produkt\/bergamottin-2\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.cfmot.de\/en\/produkt\/bergamottin-2\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.cfmot.de\/en\/"},{"@type":"ListItem","position":2,"name":"Phytochemicals","item":"https:\/\/www.cfmot.de\/en\/produktgruppe\/phytochemicals\/"},{"@type":"ListItem","position":3,"name":"Reference Substances","item":"https:\/\/www.cfmot.de\/en\/produktgruppe\/reference-substances\/"},{"@type":"ListItem","position":4,"name":"Bergamottin"}]},{"@type":"WebSite","@id":"https:\/\/www.cfmot.de\/en\/#website","url":"https:\/\/www.cfmot.de\/en\/","name":"Cfm Oskar Tropitzsch GmbH","description":"Chemikalien, Feinchemikalien, Metallverbindungen","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.cfmot.de\/en\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"}]}},"_links":{"self":[{"href":"https:\/\/www.cfmot.de\/en\/wp-json\/wp\/v2\/produkt\/64731","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.cfmot.de\/en\/wp-json\/wp\/v2\/produkt"}],"about":[{"href":"https:\/\/www.cfmot.de\/en\/wp-json\/wp\/v2\/types\/produkt"}],"version-history":[{"count":5,"href":"https:\/\/www.cfmot.de\/en\/wp-json\/wp\/v2\/produkt\/64731\/revisions"}],"predecessor-version":[{"id":80340,"href":"https:\/\/www.cfmot.de\/en\/wp-json\/wp\/v2\/produkt\/64731\/revisions\/80340"}],"wp:attachment":[{"href":"https:\/\/www.cfmot.de\/en\/wp-json\/wp\/v2\/media?parent=64731"}],"wp:term":[{"taxonomy":"produktgruppe","embeddable":true,"href":"https:\/\/www.cfmot.de\/en\/wp-json\/wp\/v2\/produktgruppe?post=64731"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}