7-Ethyl-10-hydroxycamptothecin

Artikelnummer:

5600101

CAS No.:

86639-52-3

Formel:

C22H20N2O5

Synonyme:

SN-38

Molekulargewicht:

392,40 g/mol

7-Ethyl-10-hydroxycamptothecine is the active metabolite of irinotecan. This compound is also an inhibitor of topoisomerase I. Gene expression analysis of colon cancer cell lines treated with SN-38 showed differential effects: the majority of affected genes were down-regulated.Some of the up-regulated genes were involved in apoptosis, transcription, development and differentiation.

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7-Ethyl-10-hydroxycamptothecin

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Cfm Oskar Tropitzsch GmbH ist bekannt dafür, ausgefallene Forschungsreagenzien zu liefern – in diesem Falle Cytoxoxins für Antikörper. Bei diesen „Warheads“ handelt es sich um hoch toxische Substanzen, wie z.B. ...

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