alpha-Conotoxin GI

Artikelnummer:

5250008

Formel:

C55H80N20O18S4

Chemische Beschreibung:

Sequence: [Cys2-Cys7, Cys3-Cys13 ]; H-Glu-Cys-Cys-Asn-Pro-Ala-Cys-Gly-Arg-His-Tyr-Ser-Cys-NH2

Molekulargewicht:

1437,60 g/mol

Alpha-conotoxin GI act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This conotoxin has been isolated from the venomof the cone snail C onus geographus. The higher affinity site for alpha-conotoxin GI is the alpha/delta site on mouse muscle-deriverd BC3H-1 receptor, and the other site(alpha/gamma site) on nicotinic receptors from To rpedo californica electric organ.

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alpha-Conotoxin GI