alpha-Conotoxin MI

Artikelnummer:

5250030

Formel:

C58H88N22O17S4

Chemische Beschreibung:

Sequence: [Cys3-Cys8, Cys4-Cys14]; H-Gly-Arg-Cys-Cys-His-Pro-Ala-Cys-Gly-Lys-Asn-Tyr-Ser-Cys-NH2

Molekulargewicht:

1493,70 g/mol

a-conotoxins MI has been isolated from the venom of the cone snail Conus magus. This conotoxin act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors(nAChR) and thus inhibi t them. a-conotoxins MI blocks mammalian nAChR composed of a-1/d subunits with high potency and a-1/? with a low potency.

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alpha-Conotoxin MI