IKD-8344

Article number:

5500054

CAS No.:

129046-69-1

Formula:

C20H28

Molecular weight:

268,44 g/mol

IKD-8344 is a macrocyclic dilactone originally isolated from an actinomycete species and has diverse biological activities, including anticancer, antimicrobial, and anthelmintic properties. IKD-8344 is cytotoxic to L5178Y murine leukemia cells (IC50 = 0.54 ng/ml). IKD-8344 inhibits growth of the mycelial form of C. albicans (MIC = 6.25 µg/ml) and potentiates the activity of polymyxin B against the multidrug-resistant pathogenic bacterium B. cenocepacia. Potential mode of action/Key word: Cytotoxic, Antibiotic, Anticancer

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IKD-8344

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