senetics InnovationAward 2021 for Cfm Oskar Tropitzsch GmbH
For years, senetics has promoted and supported the innovative capacity of institutes and companies in the medical technology, pharmaceutical and biotechnology industries. The “senetics Innovation Award” for the most innovative product idea was presented in 2012 for the first time. Under the patronage of the Bavarian State Ministry, the senetics expert jury gives the awards […]
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Alpine Winter Conference
Visit us at the 2nd Alpine Winter Conference in St. Anton, taking place Jan. 19.- Jan 23, 2020 The Conference topics will include: Accelerating Drug Discovery by Intelligence Augmentation Drug Discovery Tales Frontiers of Synthetic Chemistry Innovation and Inspiration from Natural Products Predictive ADME Sciences: Striking a Balance Between in Silico and Experimental Work? Protein […]
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Let`s meet in San Diego
Antibody and ADC experts are meeting in San Diego Dec. 9-13. For this reason I`m going to present a poster with the titel: “Novel Mode Of Action Molecules” which explains the inhibition of the GRP78 pathway of one of our molecules. In case you would like to arrange an appointment, don`t hesitate to reach out […]
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Meet us in San Diego
On October 10th and 11th we are going to exhibit the 5th time in a row at the World-ADC-Conference in San Diego. The event takes place at Manchester Grand Hyatt San Diego, 1 Market Pl, San Diego, CA 92101. Make sure to visit us at our booth #43 in order to stay tuned about Novel […]
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The new ADC-SD-file is available
Cfm Oskar Tropitzsch offers in addition to the classic print medium and the Internet, the so call ADCs or HPAPIs or Payloads as an SD file (Structure Data File) free to download. SD files contain not only the product name, the CAS-number, the molecular weight, synonyms but also the chemical structures of the individual substances. […]
Read moreNovel MoA Payload: OSW-1
Cfm Oskar Tropitzsch GmbH is happy to offer a new payload with a new Mode of Action (MoA). GRP78 (BiP) is the key member of the HSP70 protein family and functions as an ER chaperone involved in protein folding and assembly. Due to many cancer cells‘ inherently elevated ER stress level, GPR78 is highly expressed […]
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14th Annual Drug Discovery Chemistry
Visit Cfm Oskar Tropitzsch GmbH at Booth #: 318 14th Annual Drug Discovery Chemistry is a dynamic conference for medical chemists working in pharma and biotech. Focused on discovery and opimization challenges of small molecule drug candidates, this event provides many exciting opportunities for scientists to create a unique program to hear presenations most suited […]
Read moreBeta-Amanitin – a potential payload for antibody drug conjugates (ADCs)
beta-Amanitin is an inhibitor of eukaryotic RNA polymerase II and RNA polymerase III, but not RNA polymerase I or bacterial RNA polymerase. It inhibits mammalian protein synthesis. These properties make it interesting as a new potential drug for ADC research. α-Amanitin is already known as effective payload for ADCs. beta-Amanitin has a comparable biological activity […]
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