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4-Hydroxyphenyl-beta-D-glucopyranoside; Hydroquinone β-D-glucopyranoside; p-Hydroxyphenyl β-D-glucoside
- Is found in damiana (Turnera diffusa), cranberry, blueberry, raspberry, wheat germ, porst, round-leaved wintergreen, bearberry (minimum requirement according to the European Pharmacopoeia 7%), coffee, tea, red wine, and pears and pear leaves
- Is a chemical compound from the group of aryl-β-glucosides and hydroquinones.
- It is converted in the intestine by bacteria to glucose and hydroquinone
- Represents a prodrug as a hydroquinone glucoside
- Poorly absorbable in its original form and cannot reach its site of action in this form
Limitations of Use:
- Hydroquinone, which is derived from arbutin, has liver-damaging effects at higher doses and is suspected of having mutagenic or possibly even carcinogenic effects.
This is the reason for the restrictions in its use:
- Not more than 5 times a year and for 1 week only.
- Not during pregnancy or lactation
- Not for children
- Due to the high tannin content, arbutin-containing drugs, when prepared as a tea, nausea and vomiting is possible, so it should be prepared as a cold macerat
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