H HO OH

Avarol

Article number:

5500471

CAS No.:

55303-98-5

Formula:

C21H30O2

Molecular weight:

314,46 g/mol

Marine sponges are one of the richest sources of anticancer active compounds found in the marine ecosystems. To survive in the complicated marine environment, most of the sponge species have evolved chemical weapons to defend against predation. Such chemical adaptation produces many biologically active secondary metabolites to name one - anticancer agents. One utmost interesting compound of this sponge family is Avarol. Avarol induces apoptosis in pancreatic ductal adenocarcinoma cells by activating PERK-eIF2α-CHOP signaling. Mar. Drugs 2015, 13, 2376-2389; doi:10.3390/md13042376

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Avarol

Fermentation Products

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