Chaetoglobosin C13

Article number:

5500455

Formula:

C32H36N2O5

Molecular weight:

538,00 g/mol

This is the C13 labeled version of Chaetoglobosin A which preferentially induces apoptosis in chronic lymphocytic leukemia cells by targeting the cytoskeleton. Knudsen at al., Leukemia. 2014 Jun; 28(6):1289-98. doi: 10.1038/leu.2013.360. Epub 2013 Nov 27. Chaetoglobosin A targets filamentous actin in CLL cells and thereby induces cell-cycle arrest and inhibits membrane ruffling and cell migration. Potential mode of action/Key words: Apoptosis inducer, Targeting Tubulin

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Chaetoglobosin C13

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