Rapamycin, R&D grade

Article number:

5500427

CAS No.:

53123-88-9

Formula:

C51H79NO13

Chemical description:

(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl]-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone

Molecular weight:

914,19 g/mol

Rapamycin is a macrocyclic triene antibiotic that binds to and inhibits the molecular target of rapamycin (mTOR). Rapamycin is a potent immunosuppressant used as an alternative to calcineurin inhibitors and has anticancer activity. Sirolimus restricts the proliferation of smooth-muscle cells by blocking cell cycle progression at the G1/S transition. Addtional properties: Anti-proliferative, antitumor compound, apoptosis enhancer, anti-HIV, anti-aging. We sell this grade of Rapamycin for R&D use only!

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Rapamycin, R&D grade

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