for our newsletter!
17-AEP-GA belongs to the Geldanamycin family. It is an HSP90 inhibitor. 17-AEP-GA was shown to be a powerful inhibitor of cancer cell growth (IC50 below 100 nm). Its binding affinity to HSP90 was not significantly affected compated to Geldanamycin and other analogs while its water solubility was highly improved compated to 17-AAG. Reference: ZQ Tian et al. Bioorg. Med. Chem 2004 12:5317. Potential mode of action/Key words: HSP 90 inhibitor, Targeting HSP 90
Cfm Oskar Tropitzsch GmbH supplies unique molecules - in this case the cytotoxins for antibodies. These payloads are ultra-toxic drugs, i.e. cytotoxic and/or cytostatic molecules, effective at a low dosage and ...