17-AH-Geldanamycin

Article number:

5600054

Formula:

C34H52N4O8

Chemical description:

17-(6-aminohexylamino)-17-demethoxygeldanamycin

Synonyms:

AH-GDM; 17-AHA-Geldanamycin

Molecular weight:

644,80 g/mol

17-AH-Geldanamycin is a semi-synthetic analog of geldanamycin containing a linker bearing a free NH2 functional group for conjugation. Selectively binds to HSP90. 17-AH-Geldanamycin has been used in a copolymeric composition for sustained delivery and controlled release (1,2) as well as other applications. References: 1. MP Borgman et al. Mol. Pharm. 2009 6:1836; 2. Y Kasua et al. J. Control. Release 2001 74:203 Potential mode of action/Key words: HSP 90 inhibitor, Targeting HSP 90

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17-AH-Geldanamycin

Toxins with Linkers

Cfm Oskar Tropitzsch GmbH also provides linker-drug conjugates. Either as linker-drug conjugate or under contract synthesis arrangements. To take advantage of this service please contact us info@cfmot.de for more information. Some ...

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