NH O N NH 2 O H N O O O O O N N HN O O O N O HN O O O N N O O N

Actinomycin D

Article number:

5600133

CAS No.:

50-76-0

Formula:

C62H86N12O16

Chemical description:

2-Amino-4,6-dimethyl-3-oxo-N,N'-bis[(3R,6S,7R,10S,16S)7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadec-6-yl]phenoxazin-1,9-dicarboxamid

Synonyms:

Actinomycin IV , Actinomycin C1, Dactinomycin, Cosmegen, Actinonym IV

Molecular weight:

1255,50 g/mol

Actinomycin D induces apoptosis. It is a potent antitumor agent. Actinomycin D is used for cell culture applications as a selection agend. Origin: Streptomyces parvulus HCT-116: IC50=0,0008 µM; PSN1 : IC50=0,0008 µM; T98G : IC50=0,008 µM; A549 : IC50=0,04 µM (preliminary laboratory results). Potential mode of action/Key words: Targeting RNA, RNA-Polymerase inhibitor, Antitumoral, Induces Apoptosis

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Actinomycin D

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