OH OH H HO HO H

Aphidicolin

Article number:

5600136

CAS No.:

38966-21-1

Formula:

C20H34O4

Synonyms:

(+)-Aphidicolin

Molecular weight:

338,49 g/mol

Aphidicolin is a tetracyclic diterpene antibiotic with antiviral, antineoplastic and antimitotic properties. It is a reversible inhibitor of eukaryotic nuclear DNA replication and blocks the cell cycle at early S phase. Furthermore it is known as a specific inhibitor of DNA polymerase A,D in eukaryotic cells and in some viruses. Aphidicolin belongs to the group of mycotoxins. Origin: Nigrospora oryzae

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Aphidicolin

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