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Article number:
5600136
CAS No.:
38966-21-1
Formula:
C20H34O4
Synonyms:
(+)-Aphidicolin
Molecular weight:
338,49 g/mol
Aphidicolin is a tetracyclic diterpene antibiotic with antiviral, antineoplastic and antimitotic properties. It is a reversible inhibitor of eukaryotic nuclear DNA replication and blocks the cell cycle at early S phase. Furthermore it is known as a specific inhibitor of DNA polymerase A,D in eukaryotic cells and in some viruses. Aphidicolin belongs to the group of mycotoxins. Origin: Nigrospora oryzae
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