Apigenin

Article number:

7500745

CAS No.:

520-36-5

Formula:

C15H10O5

Chemical description:

Apigenin originally isolated from Chamomillae romana. The flavonoid has numerous pharmacological effects like anti-inflammatory, anticancer, antioxidant and antiviral activities.

Synonyms:

5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one;4',5,7-Trihydroxyflavone; Chamomile; Spigenin; Versulin

Molecular weight:

270,23 g/mol

Apigenin, a dietary flavonoid, inhibits proliferation of human bladder cancer T-24 cells via blocking cell cycle progression and inducing apoptosis.Shi MD, Shiao CK, Lee YC, Shih YW.Cancer Cell Int. 2015 Mar 29;15:33. doi: 10.1186/s12935-015-0186-0. eCollection 2015.***Apigenin Restricts FMDV Infection and Inhibits Viral IRES Driven Translational Activity. Qian S, Fan W, Qian P, Zhang D, Wei Y , Chen H, Li X.Viruses. 2015 Mar 31;7(4):1613-26. doi: 10.3390/v7041613.***Effect of Luteolin and Apigenin on the Expression of Oct-4, Sox2, and c-Myc in Dental Pulp Cells with In Vitro Culture.Liu L, Peng Z, Xu Z, Wei X.Biomed Res Int. 2015;2015:534952. doi: 10.1155/2015/534952. Epub 2015 Feb 26.***The effects of apigenin on lipopolysaccharide-induced depressive-like behavior in mice.Li R, Zhao D, Qu R, Fu Q, Ma S.Neurosci Lett. 2015 Mar 20;594:17-22. doi: 10.1016/j.neulet.2015.03.040. [Epub ahead of print]***Apigenin inhibits pancreatic stellate cell activity in pancreatitis.Mrazek AA, Porro LJ, Bhatia V, Falzon M, Spratt H, Zhou J, Chao C, Hellmich MR.J Surg Res. 2015 Feb 19. pii: S0022-4804(15)00140-7. doi: 10.1016/j.jss.2015.02.032. [Epub ahead of print]***Effect of Apigeni n on Leishmania amazonensis Is Associated with Reactive Oxygen Species Production Followed by Mitochondrial Dysfunction.Fonseca-Silva F, Canto-Cavalheiro MM, Menna-Barreto RF, Almeida-Amaral EE.J Nat Prod. 2015 Mar 13. [Epub ahead of print]***Protective effects of apigenin against 1-methyl-4-phenyl

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Apigenin

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