O O O O O O O O O OH OH HO HO HO OH O OH O O OH O H

Apoptolidin

Article number:

5500641

CAS No.:

194874-06-1

Formula:

C58H96O21

Molecular weight:

1129,37 g/mol

Apoptolidin is a F0F1-ATPase inhibitor. Apotptolidin was originally isolated from Nocardiopsis sp. Antibiotic. It is an highly selective and potent apoptosis inducer in several cancer cell lines. Apoptosis in E1A-transformed cells: IC50 = 11 ng/ml; F0F1-ATPase: IC50 = 700 nM (yeast).

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Apoptolidin

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