Aucubin

Article number:

7550650

CAS No.:

479-98-1

Formula:

C15H22O9

Chemical description:

Synonyms:

(2S,3R,4S,5S,6R)-2-[[(1S,4aR,5S,7aS)-5-hydroxy-7-(hydroxymethyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-1-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol; Aucuboside; Rhinanthin

Molecular weight:

346,33 g/mol

Aucubin prevents interleukin-1 beta induced inflammation and cartilage matrix degradation via inhibition of NF-?B signaling pathway in rat articular chondrocytes. Wang SN, Xie GP, Qin CH, Chen YR, Zhang KR, Li X, Wu Q, Dong WQ, Yang J, Yu B. Int Immunopharmacol. 2015 Feb;24(2):408-15. doi: 10.1016/j.intimp.2014.12.029. Epub 2015 Jan 6. *** Aucubin promotes neurite outgrowth in neural stem cells and axonal regeneration in sciatic nerves. Kim YM, Sim UC, Shin Y, Kim Kwon Y. Exp Neurobiol. 2014 Sep;23(3):238-45. doi: 10.5607/en.2014.23.3.238. Epub 2014 Sep 18. *** Aucubin, a naturally occurring iridoid glycoside inhibits TNF-a-induced inflammatory responses through suppression of NF-?B activation in 3T3-L1 adipocytes. Park KS.Cytokine. 2013 Jun;62(3):407-12. doi: 10.1016/j.cyto.2013.04.005. Epub 2013 Apr 20. *** Neuroprotective properties of aucubin in diabetic rats and diabetic encephalopathy rats. Xue HY, Lu YN, Fang XM, Xu YP, Gao GZ, Jin LJ. Mol Biol Rep. 2012 Oct;39(10):9311-8. doi: 10.1007/s11033-012-1730-9. Epub 2012 Jul 19.

Plant: ribwort (Plantago lanceolata), eyebright (Euphrasia), mullein (Verbascum) (woolly flower), speedwell (Veronica officinalis).

  • Secondary plant substance from the group of iridoids, it is a glycoside of the aglycone aucubigenin with one unit of glucose
  • Has antibiotic effect and influences blood pressure
  • The sap of ribwort contains aucubin and does not mold, the saps of most other plants mold
  • Aucubin has anti-inflammatory, analgesic, astringent and anti-irritant effects
  • Applying crushed ribwort leaves can reduce the itching and swelling of insect bites
  • Used for inflammation of the mouth, throat and respiratory tract and for inflammatory eye conditions (also used to improve breastfeeding performance and to treat menstrual cramps)
  • Aucubin is preserved only with careful extraction
  • It makes the tea bitter
  • Aucubin is decomposed by intestinal bacteria, so the tea has no pharmacological effect

Inform about
Aucubin

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