Auristatin E

Article number:


CAS No.:




Chemical description:


Molecular weight:

732,01 g/mol

Auristatin E is a synthetic analog of Dolastatin 10. Auristatin E is a highly potent antimitotic agent.Auristatin E inhibits tubulin polymerization(1). Auristatin E-antibody cunjugates have proven to be successful anticancer agents.(2) 1. GR Pettit et al. Anticancer Drug Des. 1995 10:529. 2. SO Doronina et al. Nature Biotechnol. 2003 21:778. Auristatin E is a Tubulin inhibitor. Potential mode of action/Key words: Targeting Tubulin, Antimitotic, Anticancer, Cytotoxic

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Auristatin E


Cfm Oskar Tropitzsch GmbH supplies unique molecules - in this case the cytotoxins for antibodies. These payloads are ultra-toxic drugs, i.e. cytotoxic and/or cytostatic molecules, effective at a low dosage and ...

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