Baclofen

Article number:

7000426

CAS No.:

1134-47-0

Formula:

C10H12ClNO2

Synonyms:

4-amino-3-(4-chlorophenyl)butanoic acid

Molecular weight:

213,66 g/mol

Baclofen is a GABA derivative that acts as an agonist at GABA-B receptors; it is commonly used in animal models to examine the effects of GABAergic neurotransmission in a variety of fields, including substance dependence, spasticity, pain, and feeding behavior. Baclofen exhibits analgesic, antinociceptive, and antiepileptic/anticonvulsant activities. Baclofen is used clinically to promote abstinence in alcohol dependent subjects, potentially mediating alcohol craving during withdrawal. This compound is also delivered intrathecally to treat spasticity and dystonia.

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Baclofen

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