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beta-Amanitin, a cyclic peptide, consisting of eight amino acids is part of the toxic peptide group of the Amanita phalloides mushroom. beta-Amanitin inhibits mammalian protein synthesis.It is an inhibitor of RNA polymerase II and III but not RNA polymerase I or bacterial RNA polymerase. Potential mode of action/Key words: Targeting RNA, RNA-Polymerase 1 & 2 inhibitor, Cytotoxic
Cfm Oskar Tropitzsch GmbH supplies unique molecules - in this case the cytotoxins for antibodies. These payloads are ultra-toxic drugs, i.e. cytotoxic and/or cytostatic molecules, effective at a low dosage and ...