beta-Amanitin

Article number:

5600026

CAS No.:

21150-22-1

Formula:

C39H53N9O15S

Chemical description:

2-[34-butan-2-yl-13-(3,4-dihydroxybutan-2-yl)-8,22-dihydroxy-2,5,11,14,27,30,33,36,39-nonaoxo-27?4-thia-3,6,12,15,25,29,32,35,38-nonazapentacyclo[14.12.11.06,10.018,26.019,24]nonatriaconta-18(26),19(24),20,22-tetraen-4-yl]acetic acid

Molecular weight:

919,95 g/mol

beta-Amanitin, a cyclic peptide, consisting of eight amino acids is part of the toxic peptide group of the Amanita phalloides mushroom. beta-Amanitin inhibits mammalian protein synthesis.It is an inhibitor of RNA polymerase II and III but not RNA polymerase I or bacterial RNA polymerase. Potential mode of action/Key words: Targeting RNA, RNA-Polymerase 1 & 2 inhibitor, Cytotoxic

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beta-Amanitin

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Cfm Oskar Tropitzsch GmbH supplies unique molecules - in this case the cytotoxins for antibodies. These payloads are ultra-toxic drugs, i.e. cytotoxic and/or cytostatic molecules, effective at a low dosage and ...

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