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Article number:
5500643
CAS No.:
7184-60-3
Formula:
C28H43NO6
Chemical description:
2-(7-cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxo-1-oxacyclooctadeca-4,6-dien-2-yl)cyclopentane-1-carboxylic acid
Synonyms:
Treponemycin
Molecular weight:
489,60 g/mol
Borrelidin is an angiogenesis inhibitor that induces apoptosis of the capillary tube-forming cells. It also displays antimalarial activity against drug-resistant Plasmodia. Borrelidin (Treponemycin) is a bacterial and eukaryal threonyl-tRNA synthetase inhibitor which is a nitrile-containing macrolide antibiotic isolated from Streptomyces rochei. Potential mode of action/Key words: Angiogenesis inhibitor, Apoptosis inducer, Antibiotic, Thr-tRNA synthetase inhibitor
Cfm Oskar Tropitzsch GmbH supplies unique molecules - in this case the cytotoxins for antibodies. These payloads are ultra-toxic drugs, i.e. cytotoxic and/or cytostatic molecules, effective at a low dosage and ...