Catalpol

Article number:

7550451

CAS No.:

2415-24-9

Formula:

C15H22O10

Synonyms:

(2S,3R,4S,5S,6R)-2-[[(1aS,1bS,2S,5aR,6S,6aS)-6-hydroxy-1a-(hydroxymethyl)-2,5a,6,6a-tetrahydro-1bH-oxireno[5,6]cyclopenta[1,3-c]pyran-2-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol;Catalpinoside; De(p- hydroxybenzoyl)catalposide

Molecular weight:

362,33 g/mol

Catalpol protects mice against renal ischemia/reperfusion injury via suppressing PI3K/Akt-eNOS signaling and inflammation.Zhu J, Chen X, Wang H, Yan Q.Int J Clin Exp Med. 2015 Feb 15;8(2):2038-44. e Collection 2015.***Potential Neurogenesis of Human Adipose-Derived Stem Cells on Electrospun Catalpol-Loaded Composite Nanofibrous Scaffolds.Guo JH, Liu Y, Lv ZJ, Wei WJ, Guan X, Guan QL, Leng ZQ, Zhao JY, Miao H, Liu J.Ann Biomed Eng. 2015 Mar 31. [Epub ahead of print]***Catalpol regulates cholinergic nerve system function through effect on choline acetyl-transferase not M receptor affinity .Wang JH, Xie H, Zhao TK, Kang B.Biomed Pharmacother. 2015 Feb;69:291-6. doi: 10.1016/j.biopha.2014.12.014. Epub 2014 Dec 19.***Catalpol: a potential therapeutic for neurodegenerative diseases.Ji ang B, Shen RF, Bi J, Tian XS, Hinchliffe T, Xia Y.Curr Med Chem. 2015;22(10):1278-91.***Catalpol Inhibited the Proliferation of T24 Human Bladder Cancer Cells by Inducing Apoptosis Through the Blo ckade of Akt-Mediated Anti-apoptotic Signaling.Jin D, Cao M, Mu X, Yang G, Xue W, Huang Y, Chen H.Cell Biochem Biophys. 2014 Nov 12. [Epub ahead of print]***Catalpol suppresses proliferation and f acilitates apoptosis of OVCAR-3 ovarian cancer cells through upregulating microRNA-200 and downregulating MMP-2 expression.Gao N, Tian JX, Shang YH, Zhao DY, Wu T.Int J Mol Sci. 2014 Oct 24;15(11):1 9394-405. doi: 10.3390/ijms151119394.

Plant:
Isolated from the plant Catalpa bignonioides (Bignoniaceae), native to North America and East Asia.

  • Catalpol occurs predominantly as esters of various aromatic carboxylic acids
  • Is the most abundant iridoid glucoside besides aucubin

Inform about
Catalpol

Secondary Plant Ingredients

Secondary metabolites in plants are active plant ingredients, also called phytochemicals.. The demand for Phytochemicals is constantly growing not only for reference substances (for quality tests) , but for high purity ...

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