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Chaetocin is an antitumor antibiotic. It is a thiodioxopiperazine natural product produced by Chaetomium species. Specific inhibitor of the lysine-specific methyltransferase SU. It displays potent antimyeloma activity in IL-6-dependent myeloma cell lines. Its antimyeloma activity appears to be due to induction of oxidative stress and consequent apoptosis. Potential mode of action/Key words: ROS generation, Apoptosis inducer, Antibiotic, Antitumoral
Cfm Oskar Tropitzsch GmbH supplies unique molecules - in this case the cytotoxins for antibodies. These payloads are ultra-toxic drugs, i.e. cytotoxic and/or cytostatic molecules, effective at a low dosage and ...
What does fermentation mean? Fermentation (from latin fermentare) is generally defined as a conversion of material under aerobic or anaerobic conditions influenced by micro-organisms. "Micro-organism" is a collective term for usually ...