NH O O O O N H OH H H H

Chaetoglobosin A

Article number:

5500645

CAS No.:

50335-03-0

Formula:

C32H36N2O5

Chemical description:

(1R,3E,6R,7E,9S,11E,13R,14S,16R,17S,18R,19S)-6-hydroxy-19-(1H-indol-3-ylmethyl)-7,9,16,17-tetramethyl-15-oxa-20-azatetracyclo[11.8.0.01,18.014,16]henicosa-3,7,11-triene-2,5,21-trione

Synonyms:

3H-Cyclotridec[d]oxireno[f]isoindole-8,11,12(13H)-trione,4,7,14,14a,15,15a,16a,16b-octahydro-7-hydroxy-14-(1H-indol3-ylmethyl)-4,6

Molecular weight:

528,65 g/mol

Chaetoglobosin A preferentially induces apoptosis in chronic lymphocytic leukemia cells by targeting the cytoskeleton/filamentous actin. Knudsen at al., Leukemia. 2014 Jun; 28(6):1289-98. doi: 10.1038/leu.2013.360. Epub 2013 Nov 27. Potential mode of action/Key words: Apoptosis by targeting the sytoskeleton, Targeting Actin

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Chaetoglobosin A

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