NH HN N NH O O O O (CH 2 ) 5 O O

Chlamydocin

Article number:

5600137

CAS No.:

53342-16-8

Formula:

C28H38N4O6

Chemical description:

2-Methylcyclo[Ala-L-Phe-D-Pro-6-[(S)-2-oxo-2-oxiranylethyl]-L-Nle-];Cyclo[2-methylalanyl-L-phenylalanyl-D-prolyl-(aS,2S)-a-amino-h-oxo-2-oxiraneoctanoyl]

Molecular weight:

526,64 g/mol

Chlamydocin is a cyclic tetrapeptide. Chlamydocin is a very potent inhibitor of cell proliferation. Chlamydocin was shown to be a very potent histone deacetylase (DDAC) inhibitor with an IC50 value of 1.3 nM. Some data also indicate a potential link between degradation of surviving and activation of the apoptotic pathway induced by HDAC inhibitors. Potential mode of action/Key words: Targeting DNA, HDAC inhibitor, Anticancer, Induces Apoptosis

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Chlamydocin

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Cfm Oskar Tropitzsch GmbH supplies unique molecules - in this case the cytotoxins for antibodies. These payloads are ultra-toxic drugs, i.e. cytotoxic and/or cytostatic molecules, effective at a low dosage and ...

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