NH HN N NH O O O O (CH 2 ) 5 O O


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Chemical description:


Molecular weight:

526,64 g/mol

Chlamydocin is a cyclic tetrapeptide. Chlamydocin is a very potent inhibitor of cell proliferation. Chlamydocin was shown to be a very potent histone deacetylase (DDAC) inhibitor with an IC50 value of 1.3 nM. Some data also indicate a potential link between degradation of surviving and activation of the apoptotic pathway induced by HDAC inhibitors. Potential mode of action/Key words: Targeting DNA, HDAC inhibitor, Anticancer, Induces Apoptosis

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