Cytisine

Article number:

7500679

CAS No.:

485-35-8

Formula:

C11H14N2O

Synonyms:

Baptitoxin; Laburnin; Sophorine; Ulexine

Molecular weight:

190,25 g/mol

Cytisine modulates chronic voluntary ethanol consumption and ethanol-induced striatal up-regulation of ΔFosB in mice. Sajja RK, Rahman S. Alcohol. 2013 Jun;47(4):299-307. doi: 10.1016/j.alcohol.2013.02.003. Epub 2013 Apr 17. *** Cytisine confers neuronal protection against excitotoxic injury by down-regulating GluN2B-containing NMDA receptors. Li YJ, Yang Q, Zhang K, Guo YY, Li XB, Yang L, Zhao MG, Wu YM. Neurotoxicology. 2013 Jan;34:219-25. doi: 10.1016/j.neuro.2012.09.009. Epub 2012 Sep 26. *** Cytisine, a partial agonist of high-affinity nicotinic acetylcholine receptors, has antidepressant-like properties in male C57BL/6J mice. Mineur YS, Somenzi O, Picciotto MR. Neuropharmacology. 2007 Apr;52(5):1256-62. Epub 2007 Jan 20. *** C3-halogenation of cytisine generates potent and efficacious nicotinic receptor agonists. Abin-Carriquiry JA, Voutilainen MH, Barik J, Cassels BK, Iturriaga-Vásquez P, Bermudez I, Durand C, Dajas F, Wonnacott S. Eur J Pharmacol. 2006 Apr 24;536(1-2):1-11. Epub 2006 Mar 6.

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