Daunorubicin HCl

Article number:

5600016

CAS No.:

23541-50-6

Formula:

C27H30ClNO10

Synonyms:

Daunomycin

Molecular weight:

563,98 g/mol

Daunorubicin HCl is a chemotherapeutic of the anthracycline family. It is mainly used to treat acute myeloid leukemia and acute lymphocytic leukemia. The biochemical mode of action is the inhibition of DNA and RNA synthesis as sequence specific ds-DNA interacting agent. Daunomycin binds to every 3 base pairs and induces a local unwinding angel of 8°C. K562 (Erythroleukemia cells): IC50 = 15 nM (human); NHDF: IC50 = 190 nM (human). pKa: 7.39, pKb: 8.68.

Inform about
Daunorubicin HCl

Fermentation Products

What does fermentation mean? Fermentation (from latin fermentare) is generally defined as a conversion of material under aerobic or anaerobic conditions influenced by micro-organisms. "Micro-organism" is a collective term for usually ...

Read more