Dolastatin 15

Article number:

5600002

CAS No.:

123884-00-4

Formula:

C45H68N6O9

Chemical description:

[(2S)-1-[(2S)-2-benzyl-3-methoxy-5-oxo-2H-pyrrol-1-yl]-3-methyl-1-oxobutan-2-yl] (2S)-1-[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-(dimethylamino)-3-methylbutanoyl]amino]-3-methylbutanoyl]-methylamino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-car

Molecular weight:

836,06 g/mol

Dolastatin 15 may be a useful tubulin-targeting payload for the conjugation at various antibody reactive sites, depending on the used linker technology. IC50 value 23 µM (Bai et al. 1992). Dolastatin 15 is a Tubulin inhibitor. Potential mode of action/Key words: Targeting Tubulin, Induces Apoptosis

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Dolastatin 15

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Cfm Oskar Tropitzsch GmbH supplies unique molecules - in this case the cytotoxins for antibodies. These payloads are ultra-toxic drugs, i.e. cytotoxic and/or cytostatic molecules, effective at a low dosage and ...

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