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DOX; Hydroxydaunorubicinhydrochloride; Adrimycin(R)hydrochloride; Adriacin; Adriamycin; Adriblastin; Caelyx; Doxil; Myocet
Doxorubicin is a DNA intercalator and broad-spectrum antitumor agent, shown to downregulate expression of the oncogenes c-Jun and c-Myc, inhibit Topoisomerase II.
Selman Waksman defined the term antibiotic in 1942 to describe any substance produced by a microorganism that is antagonistic to the growth of other microorganisms in high dilution. While this ...