N OH Cl NH O O N O OH F F F

Duocarmycin DM

Article number:

5600183

Formula:

C28H27ClF3N3O5

Molecular weight:

577.98 g/mol

Duocarmycin DM, a DNA minor-groove alkylator, is an antibody drug conjugates toxin. It is based on its characteristic curved indole structure and a spirocyclopropylcyclohexadienone electrophile to act anticancer activity. Potential mode of action/Key words: Targeting DNA, DNA alkylator, Anticancer

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Duocarmycin DM

ADCs

Cfm Oskar Tropitzsch GmbH supplies unique molecules - in this case the cytotoxins for antibodies. These payloads are ultra-toxic drugs, i.e. cytotoxic and/or cytostatic molecules, effective at a low dosage and ...

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