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Duocarmycin DM, a DNA minor-groove alkylator, is an antibody drug conjugates toxin. It is based on its characteristic curved indole structure and a spirocyclopropylcyclohexadienone electrophile to act anticancer activity
Cfm Oskar Tropitzsch GmbH supplies unique molecules - in this case the cytotoxins for antibodies. These payloads are ultra-toxic drugs, i.e. cytotoxic and/or cytostatic molecules, effective at a low dosage and ...