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Dxd-D5 is a deuterium labeled Dxd. It is a potent DNA topoisomerase I inhibitor, with an IC50 of 0.31 µM, used as a conjugated drug of HER2-targeting ADC. Potential mode of action/Key words: Targeting DNA, DNA topoisomerase I inhibitor
Cfm Oskar Tropitzsch GmbH supplies unique molecules - in this case the cytotoxins for antibodies. These payloads are ultra-toxic drugs, i.e. cytotoxic and/or cytostatic molecules, effective at a low dosage and ...