Echinacoside

Echinacoside induces rat pulmonary artery vasorelaxation by opening the NO-cGMP-PKG-BKCa channels and reducing intracellular Ca(2+) levels.Gai XY, Wei YH, Zhang W, Wuren TN, Wang YP, Li ZQ, Liu S, Ma L, Lu DX, Zhou Y, Ge RL.Acta Pharmacol Sin. 2015 May;36(5):587-96. doi: 10.1038/aps.2014.126. Epub 2015 Apr 13.***Echinacoside Protects against 6-Hydroxydopamine-Induced Mitochondrial Dysfunction and Inflammatory Responses in PC12 Cells via Reducing ROS Production.Wang YH, Xuan ZH, Tian S, Du GH.Evid Based Complement Alternat Med. 2015;2015:189239. doi: 10.1155/2015/189239. Epub 2015 Feb 18. ***Echinacoside improves hematopoietic function in 5-FU-induced myelosuppression mice.Wang S, Zheng G, Tian S, Zhang Y, Shen L, Pak Y, Shen Y, Qian J.Life Sci. 2015 Feb 15;123:86-92. doi: 10.1016/ j.lfs.2015.01.002. Epub 2015 Jan 23.***Antiproliferative effect of echinacoside on rat pulmonary artery smooth muscle cells under hypoxia.Gai XY, Tang F, Ma J, Zeng KW, Wang SL, Wang YP, Wuren TN, Lu DX, Zhou Y, Ge RL.J Pharmacol Sci. 2014;126(2):155-63.***Echinacoside inhibits amyloid fibrillization of HEWL and protects against Aß-induced neurotoxicity.Zhang D, Li H, Wang JB.Int J Biol Ma cromol. 2015 Jan;72:243-53. doi: 10.1016/j.ijbiomac.2014.08.034. Epub 2014 Sep 2.***Echinacoside ameliorates D-galactosamine plus lipopolysaccharide-induced acute liver injury in mice via inhibition of apoptosis and inflammation.Li X, Gou C, Yang H, Qiu J, Gu T, Wen T.Scand J Gastroenterol. 2014 A