O O O N HO S OH O H

Epothilone B

Article number:

5600140

CAS No.:

152044-54-7

Formula:

C27H41NO6S

Chemical description:

(1S,3S,7S,10R,11S,12S,16R)-7,11-dihydroxy-8,8,10,12,16-pentamethyl-3-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione

Synonyms:

Patupilone

Molecular weight:

507,68 g/mol

Microtubule stabilization agent that promotes tubulin polymerization and induces G2-M cell cycle arrest. Inhibits a variety of human cancer cell lines, including MDR cells overexpressing the P-glycoprotein efflux pump. Exhibits potent anticancer activity in numerous human tumor xenografts in vivo. Epothilone B is a Tubulin inhibitor. Potential mode of action/Key words: Targeting Tubulin, Tubulin inhibitor, Anticancer, Induces Apoptosis

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Epothilone B

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