epsilon-Amanitin

Article number:

5600028

CAS No.:

21705-02-2

Formula:

C39H53N9O14S

Chemical description:

2-[34-butan-2-yl-8,22-dihydroxy-13-(3-hydroxybutan-2-yl)-2,5,11,14,27,30,33,36,39-nonaoxo-27?4-thia-3,6,12,15,25,29,32,35,38-nonazapentacyclo[14.12.11.06,10.018,26.019,24]nonatriaconta-18(26),19(24),20,22-tetraen-4-yl]acetic acid

Molecular weight:

903,96 g/mol

epsilon-Amanitin is a cyclic peptide, found i.e. in the Amanita genus of mushrooms. Oral LD50 is in the range of 0.1 mg/kg. Inhibits the activity of RNA polymerase II. Potential mode of action/Key words: Targeting RNA, RNA-Polymerase 1 & 2 inhibitor, Cytotoxic

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epsilon-Amanitin

ADCs

Cfm Oskar Tropitzsch GmbH supplies unique molecules - in this case the cytotoxins for antibodies. These payloads are ultra-toxic drugs, i.e. cytotoxic and/or cytostatic molecules, effective at a low dosage and ...

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