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LL-Z-1640-2 is a resocrcylic lactone of fungal origin that acts as a pontent and selective transforming growth factor-ß-activated kinase 1 (TAK1) mitogen-activated protein kinase kinase kinase (MAPKKK) inhibitor (IC50=8 nM). Inhibits production of inflammatory mediators, and sensitztes cells to TRAIL- and TNF-Alpha-induced apoptosis in vitro.
What does fermentation mean? Fermentation (from latin fermentare) is generally defined as a conversion of material under aerobic or anaerobic conditions influenced by micro-organisms. "Micro-organism" is a collective term for usually ...