Mensacarcin

Article number:

5500137

CAS No.:

808750-39-2

Formula:

C21H24O9

Chemical description:

(1S,9S,10S,11S,12S,13S,14R)-11,12,14-trihydroxy-7,9-dimethoxy-13-methyl-12-[(2R,3S)-3-methyloxirane-2-carbonyl]-15-oxatetracyclo[8.4.1.01,10.03,8]pentadeca-3(8),4,6-trien-2-one

Molecular weight:

420,4 g/mol

Mensacarcin is an antitumor compound. Mensacarcin has cytotoxic activity (TGI 1.3 µM, NCI standard). Furthermore Mensacarcin is described as an antibiotic compound. Mensacarcin is isolated from Streptomyces bottropensis. Mensacarcin targets mitochondria, affects energy metabolism in mitochondria, and activates caspase-dependent apoptotic pathways. Mensacarcin, an antibiotic, can be used as a cytotoxic component of antibody-drug conjugates (ADCs). Potential mode of action/Key words: Cytotoxic Antibiotic, Apoptosis Inducer

Inform about
Mensacarcin

ADCs

Cfm Oskar Tropitzsch GmbH supplies unique molecules - in this case the cytotoxins for antibodies. These payloads are ultra-toxic drugs, i.e. cytotoxic and/or cytostatic molecules, effective at a low dosage and ...

Read more

Antibiotics

Selman Waksman defined the term antibiotic in 1942 to describe any substance produced by a microorganism that is antagonistic to the growth of other microorganisms in high dilution. While this ...

Read more

Fermentation Products

What does fermentation mean? Fermentation (from latin fermentare) is generally defined as a conversion of material under aerobic or anaerobic conditions influenced by micro-organisms. "Micro-organism" is a collective term for usually ...

Read more