N H NH N O O N O O O HN O O O

MMAF-OMe

Article number:

5600190

CAS No.:

863971-12-4

Formula:

C40H67N5O8

Molecular weight:

745,99 g/mol

MMAF-Ome, an antitubulin agent, is also an ADC cytotoxin. It inhibits several tumor cell lines with IC50s of 0.056 nM, 0.166 nM, 0.183 nM, and 0.449 nM for MDAMB435/5T4, MDAMB361DYT2, MDAMB468, and Raji (5T4-) cell lines, respectively.

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MMAF-OMe

ADCs

Cfm Oskar Tropitzsch GmbH supplies unique molecules - in this case the cytotoxins for antibodies. These payloads are ultra-toxic drugs, i.e. cytotoxic and/or cytostatic molecules, effective at a low dosage and ...

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