OH OH O H 2 N OH OH O

Myriocin

Article number:

5500931

CAS No.:

35891-70-4

Formula:

C21H39NO6

Chemical description:

(2S,3R,4R,6E)-2-Amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic acid

Synonyms:

Thermozymocidin, ISP-I

Molecular weight:

401,54 g/mol

Myriocin is a fungal metabolite with potent immunosuppressant activity. Inhibits serine palmitoyltransferase at picomolar concentrations blocking synthesis of ceramide, a precursor of sphingomyelin and glycosphingolipids. Myriocin belongs to the group of mycotoxins. Origin: Mycelia sterilia (fungus)

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Myriocin

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