Netropsin Dihydrochloride

Article number:

5500560

CAS No.:

18133-22-7

Formula:

C18H26N10O3*2HCl

Synonyms:

Congocidin, Sinanomycin

Molecular weight:

503,39 g/mol

Netropsin, isolated from Streptomyces netropsis is an unusual n-methylpyrrole-containing oligopeptide that binds to the AT-rich sequences of dsDNA, especially in the minor groove. It protects therefore regions from DNase I and other endonucleases, and also inhibits topoisomerases. Netropsin disrupts the cell cycle, prolonging G and arresting in G.

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Netropsin Dihydrochloride

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