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Article number:
5500653
CAS No.:
33069-62-4
Formula:
C47H51NO14
Chemical description:
[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-diacetyloxy-15-[(2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl]oxy-1,9-dihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate
Synonyms:
Taxol
Molecular weight:
853,92 g/mol
Paclitaxel is an antineoplastic agent from a plant extract. It stabilizes microtubules in their polymerized form thus leading to cell death. A new study seems to confirm, that Taxol is supporting the regeneration after spinal cord injury. Original publication: Farida Hellal et al.: "Microtubule stabilization reduces scarring and causes axon regeneration after spinal cord injury"; Science online publicaiton, January 27th 2011. Potential mode of action/Key words: Targeting Tubulin, Induces Apoptosis, Promotes Tubulin assembly
Cfm Oskar Tropitzsch GmbH supplies unique molecules - in this case the cytotoxins for antibodies. These payloads are ultra-toxic drugs, i.e. cytotoxic and/or cytostatic molecules, effective at a low dosage and ...
What does fermentation mean? Fermentation (from latin fermentare) is generally defined as a conversion of material under aerobic or anaerobic conditions influenced by micro-organisms. "Micro-organism" is a collective term for usually ...