O O O O OH O O O HO NH OH O O O O

Paclitaxel

Article number:

5500653

CAS No.:

33069-62-4

Formula:

C47H51NO14

Chemical description:

[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-diacetyloxy-15-[(2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl]oxy-1,9-dihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate

Synonyms:

Taxol

Molecular weight:

853,92 g/mol

Paclitaxel is an antineoplastic agent from a plant extract. It stabilizes microtubules in their polymerized form thus leading to cell death. A new study seems to confirm, that Taxol is supporting the regeneration after spinal cord injury. Original publication: Farida Hellal et al.: "Microtubule stabilization reduces scarring and causes axon regeneration after spinal cord injury"; Science online publicaiton, January 27th 2011. Potential mode of action/Key words: Targeting Tubulin, Induces Apoptosis, Promotes Tubulin assembly

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Paclitaxel

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