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Phalloidin is a bicyclic heptapeptide toxin of the death cap mushroom toxin family aslo called phallotoxins. Phalloidin binds F-actin, preventing its depolymerization and is poisoning the cell. It specially binds at the inferface between F-acting subunits, locking adjacent subunites togeter. Phalloidin binds specifically to polymeric and oligomeric forms of actin and not to monomeric actin. Potential mode of action/Key words: Depolymerisation of F-actin, Targeting Actin
Cfm Oskar Tropitzsch GmbH supplies unique molecules - in this case the cytotoxins for antibodies. These payloads are ultra-toxic drugs, i.e. cytotoxic and/or cytostatic molecules, effective at a low dosage and ...