Phalloidin

Article number:

5600030

CAS No.:

17466-45-4

Formula:

C35H48N8O11S

Chemical description:

28-(2,3-dihydroxy-2-methylpropyl)-18-hydroxy-34-(1-hydroxyethyl)-23,31-dimethyl-12-thia-10,16,22,25,27,30,33,36-octazapentacyclo[12.11.11.03,11.04,9.016,20]hexatriaconta-3(11),4,6,8-tetraene-15,21,24,26,29,32,35-heptone

Molecular weight:

788,87 g/mol

Phalloidin is a bicyclic heptapeptide toxin of the death cap mushroom toxin family aslo called phallotoxins. Phalloidin binds F-actin, preventing its depolymerization and is poisoning the cell. It specially binds at the inferface between F-acting subunits, locking adjacent subunites togeter. Phalloidin binds specifically to polymeric and oligomeric forms of actin and not to monomeric actin. Potential mode of action/Key words: Depolymerisation of F-actin, Targeting Actin

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Phalloidin

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Cfm Oskar Tropitzsch GmbH supplies unique molecules - in this case the cytotoxins for antibodies. These payloads are ultra-toxic drugs, i.e. cytotoxic and/or cytostatic molecules, effective at a low dosage and ...

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