N O OH O OH

Piericidin A

Article number:

5600143

CAS No.:

2738-64-9

Formula:

C25H37NO4

Chemical description:

2-[(2E,5E,7E,9R,10R,11E)-10-Hydroxy-3,7,9,11-tetramethyl-2,5,7,11-tridecatetraen-1-yl]-5,6-dimethoxy-3-methyl-4(1H)-pyridinone

Synonyms:

Shaoguanmycin B

Molecular weight:

415,60 g/mol

Potent inhibitor of the mitochondrial and bacterial type I NADH-ubiquinone oxireductase. HCT-116: IC50=0,020 µM; PSN1 : IC50=12,03 µM; T98G : IC50=>12,03 µM; A549 : IC50=>12,03 µM (preliminary laboratory results). Journal of cellular physiology (2008), 215(1), 243-50. Potential mode of action/Key words: NADH-ubiquinone oxidoreductase (complex II) inhibitor, Cytotoxic, Anticancer

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Piericidin A

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